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In addition, we investigated the metabolic fate of U- 13 C glutamine, which produces -GC and GSH containing five 13 C atoms via GSH de novo synthesis (Fig

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It has been reported that oral administration of glutathione did not change the levels of glutathione and glutathione disulfide in the deproteinized fraction of blood, and it has been suggested that orally administered glutathione is degraded into constituting amino acids and does not exert specific activity beyond the amino acid source. Yasushi Honda et al

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